What constitutes an appropriate primary series of tetanus-containing vaccine for an adult with no documented primary vaccination?

The appropriate primary series of tetanus-containing vaccine for an adult with no documented primary vaccination is to administer one dose of Tdap, followed by Td. This approach is recommended because Tdap not only covers tetanus and diphtheria but also provides protection against pertussis, which is especially important for adults who may be in contact with infants. Administering Tdap as the initial dose ensures that the individual receives comprehensive protection while starting their vaccination series.

Following the Tdap dose, a Td booster is given to maintain immunity against tetanus and diphtheria. The Td vaccine is recommended for subsequent doses as it does not include pertussis, which is not necessary in adults after the primary series has been completed. This method ensures that adults get the most significant benefits from their immunization while following the guidelines set forth by health authorities.

For individuals with no documented primary vaccination, the selection of Tdap as the initial dose aligns with the current best practices and recommendations for adult vaccinations. This series helps to ensure that immunity is established effectively and efficiently.