Which of the following statements about live vaccines is TRUE?

Study for the APhA Immunization Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your certification!

Live vaccines are known to elicit a stronger immune response compared to inactivated vaccines. This is because live vaccines contain a weakened form of the pathogen, allowing the immune system to recognize and respond to the antigens present in a way that mimics a natural infection. The immune response generated includes both antibody production and cellular immunity, leading to a more robust and enduring immune response. This is a fundamental principle in immunology, as the body's memory response is often more potent following exposure to a live attenuated organism.

In contrast, inactivated vaccines typically produce a weaker immune response because they do not replicate or mimic an infection in the same way as live vaccines. They require adjuvants to enhance the immune response and often necessitate multiple doses for adequate immunity.

The other statements do not hold true in the context of live vaccines. Live vaccines are generally avoided in immunocompromised patients due to the risk of causing disease in individuals with weakened immune systems. Storing live vaccines at room temperature can compromise their efficacy; they typically require refrigeration to maintain their potency. Additionally, live vaccines are generally recommended to be avoided during pregnancy due to potential risks to the fetus, as the live pathogen, even weakened, could pose a threat.

Understanding these aspects helps clarify

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