Who should NOT receive the live attenuated influenza vaccine (LAIV)?

The live attenuated influenza vaccine (LAIV) is designed for healthy individuals to provide protection against influenza. It contains weakened viruses that can trigger an immune response without causing the disease itself. However, it is contraindicated for individuals with weakened immune systems, such as those with certain immunocompromising conditions, as they may be at risk for more significant complications if exposed to the attenuated virus in the vaccine.

In contrast, healthy adults and children over the age of 2 are typically considered good candidates for LAIV due to their ability to tolerate the live attenuated vaccine without increased risk of adverse effects. Pregnant women are generally advised to receive an inactivated influenza vaccine instead of the live version due to potential risks to the developing fetus and the need for caution during pregnancy. Understanding these distinctions is crucial when determining suitable candidates for the LAIV, which is primarily aimed at healthy populations.